{"created":"2023-06-20T15:14:16.637265+00:00","id":1073,"links":{},"metadata":{"_buckets":{"deposit":"b26e2f3a-9308-4d1c-a593-19e47ae5b9b9"},"_deposit":{"created_by":7,"id":"1073","owners":[7],"pid":{"revision_id":0,"type":"depid","value":"1073"},"status":"published"},"_oai":{"id":"oai:matsumoto-u.repo.nii.ac.jp:00001073","sets":["1:106"]},"author_link":["579"],"item_2_alternative_title_1":{"attribute_name":"その他（別言語等）のタイトル","attribute_value_mlt":[{"subitem_alternative_title":"Correlations of Fat Intake, Obesity, Plasma Concentration of GLP-1, and Fatty Acid Receptor in Japanese"}]},"item_2_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2018-03-12","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"90","bibliographicPageStart":"83","bibliographicVolumeNumber":"16","bibliographic_titles":[{"bibliographic_title":"松本大学研究紀要"},{"bibliographic_title":"The Journal of Matsumoto University","bibliographic_titleLang":"en"}]}]},"item_2_description_19":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_2_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"遊離脂肪酸をリガンドとするG タンパク質共役型受容体GPR120の一塩基多型（R270H）の肥満への影響が報告されている。しかし、日本人におけるこの多型の肥満との関連や、脂質摂取量等の栄養素摂取状況とこの多型の関連は不明である。そこで、この多型と日本人の肥満の関連を探るため、過去に減量指導を行ったBody Mass Intex（BMI）25以上の者24名を対象とし、GPR120（R270H）の解析を行うと共に血漿レプチンならびにGLP-1濃度を定量した。食事摂取状況はBDHQ を用いて分析した。血漿レプチン濃度はH 型ホモで4265pg/L、H 型ホモの被験者に最も近いBMI を持つR型ホモ2名で9001～10761pg/L とH 型ホモが低かったが、血漿GLP-1濃度はH 型ホモが5.4pmol/L に対しR 型ホモで6.42～6.72pmol/L と大きな違いは見られなかった。BDHQ からはH 型ホモにおいてR 型ホモよりも過食が示唆されたが、今回の対象者においては、GPR120を介して分泌されるGLP-1は両者で分泌量に違いが少なく、血漿レプチン低値等他の理由が示唆された。","subitem_description_type":"Abstract"}]},"item_2_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"学校法人松商学園松本大学"}]},"item_2_source_id_11":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AA11824385","subitem_source_identifier_type":"NCID"}]},"item_2_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"1348-0618","subitem_source_identifier_type":"ISSN"}]},"item_2_version_type_20":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"沖嶋, 直子"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2018-05-14"}],"displaytype":"detail","filename":"matsu_kiyo_16-07.pdf","filesize":[{"value":"1.3 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"matsu_kiyo_16-07.pdf","url":"https://matsumoto-u.repo.nii.ac.jp/record/1073/files/matsu_kiyo_16-07.pdf"},"version_id":"d91cd2a5-9922-44ca-aadd-5e16dd744759"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"GPR120（R270H）","subitem_subject_scheme":"Other"},{"subitem_subject":"肥満","subitem_subject_scheme":"Other"},{"subitem_subject":"脂質摂取量","subitem_subject_scheme":"Other"},{"subitem_subject":"GLP-1","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"日本人における、脂肪酸受容体変異と脂質摂取量、肥満およびGLP-1分泌量の関連について","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"日本人における、脂肪酸受容体変異と脂質摂取量、肥満およびGLP-1分泌量の関連について"}]},"item_type_id":"2","owner":"7","path":["106"],"pubdate":{"attribute_name":"公開日","attribute_value":"2018-05-14"},"publish_date":"2018-05-14","publish_status":"0","recid":"1073","relation_version_is_last":true,"title":["日本人における、脂肪酸受容体変異と脂質摂取量、肥満およびGLP-1分泌量の関連について"],"weko_creator_id":"7","weko_shared_id":-1},"updated":"2023-06-20T15:30:33.880781+00:00"}